Albumin IV Fluid Composition & Specialty Fluids Chart

Colloid and specialty-fluid comparison

Fluid	Osmolarity (mOsm/L)	Na+ (mEq/L)	Glucose	Tonicity	Primary use
D5W	252	0	50 g/L dextrose	Isotonic in the bag, physiologically hypotonic after dextrose metabolism	Free-water replacement or maintenance when you want dextrose without sodium.
D5NS	560	154	50 g/L dextrose	Hypertonic	Maintenance / replacement fluid when you want dextrose plus full normal-saline sodium and chloride content.
D5LR	525	130	50 g/L dextrose	Hypertonic in the bag	Dextrose-containing balanced crystalloid option when LR-type electrolytes are desired.
Albumin 5%	~300	≈145	0	Iso-oncotic / isotonic colloid	Plasma-volume expansion with roughly a 1:1 intravascular volume effect in an adequately hydrated patient.
Albumin 25%	~300	≈145	0	Hyperoncotic colloid	Draws interstitial water into the vasculature; the classic 3-4:1 expansion heuristic depends on capillary permeability and hydration.

Fluid	Osmolarity (mOsm/L)	Na+ (mEq/L)	Glucose	Tonicity	Primary use
D5W	252	0	50 g/L dextrose	Isotonic in the bag, physiologically hypotonic after dextrose metabolism	Free-water replacement or maintenance when you want dextrose without sodium.
D5NS	560	154	50 g/L dextrose	Hypertonic	Maintenance / replacement fluid when you want dextrose plus full normal-saline sodium and chloride content.
D5LR	525	130	50 g/L dextrose	Hypertonic in the bag	Dextrose-containing balanced crystalloid option when LR-type electrolytes are desired.
Albumin 5%	~300	≈145	0	Iso-oncotic / isotonic colloid	Plasma-volume expansion with roughly a 1:1 intravascular volume effect in an adequately hydrated patient.
Albumin 25%	~300	≈145	0	Hyperoncotic colloid	Draws interstitial water into the vasculature; the classic 3-4:1 expansion heuristic depends on capillary permeability and hydration.