Report a bugEmail support

Coagulation & Hematology

Coagulation Factors

Coagulation Factor Names & Numbers

Coagulation factors chart covering Factor I through XIII, vitamin K-dependent factors, and high-yield clotting-factor functions for anesthesia boards.

13 items~7 minutesflashcard

Reference

Review the core table first, then launch practice to convert recognition into faster recall.

Coagulation factor names and functions

Factor #	Name	Pathway	Function
I	Fibrinogen	Common	Thrombin cleaves fibrinogen into fibrin monomers that form the clot scaffold.
II	Prothrombin	Common	Precursor of thrombin, the enzyme that converts fibrinogen to fibrin and amplifies coagulation.
III	Tissue factor (thromboplastin)	Extrinsic trigger	Exposed at tissue injury and complexes with Factor VII/VIIa to start the extrinsic pathway.
IV	Calcium	Cofactor in intrinsic, extrinsic, and common pathways	Required for multiple coagulation enzyme-complex reactions on phospholipid surfaces.
V	Proaccelerin (labile factor)	Common	Cofactor for Xa in the prothrombinase complex that accelerates thrombin generation.
VII	Proconvertin (stable factor)	Extrinsic	Activated by tissue factor and helps activate Factor X.
VIII	Antihemophilic factor A	Intrinsic	Cofactor for IXa in the intrinsic tenase complex that activates Factor X.
IX	Christmas factor	Intrinsic	Serine protease that pairs with VIIIa to activate Factor X.
X	Stuart-Prower factor	Common	Central convergence factor that becomes Xa and converts prothrombin to thrombin.
XI	Plasma thromboplastin antecedent	Intrinsic	Activated by XIIa and then activates Factor IX.
XII	Hageman factor	Intrinsic/contact pathway	Contact factor that initiates the intrinsic pathway in vitro after exposure to negatively charged surfaces.
XIII	Fibrin-stabilizing factor	Common/final clot stabilization	Cross-links fibrin strands and strengthens the final clot.

Vitamin K-dependent factors

Group	Factors
Vitamin K-dependent clotting factors	II, VII, IX, X
Vitamin K-dependent natural anticoagulants	Protein C, Protein S

Citations

Barash, Clinical Anesthesia, 9th Ed — perioperative hemostasis and coagulation factor review.
Nagelhout & Elisha, Nurse Anesthesia, 7th Ed — clotting factors and coagulation cascade summary.

This tool is for educational purposes only. Always verify clinical values against current authoritative sources before patient care.